A line-of-sight towards the Galactic Center (GC) offers the largest number of potentially habitable systems of any direction in the sky. The Breakthrough Listen program is undertaking the most sensitive and deepest targeted SETI surveys towards the GC. Here, we outline our observing strategies with Robert C. Byrd Green Bank Telescope (GBT) and Parkes telescope to conduct 600 hours of deep observations across 0.7--93 GHz.